California Blood Bank Society Annual Meeting 2022

California Blood Bank Society Annual Meeting 2022

Format: 2 videos + 1 pdf, size: 6.36 GB

Course Audience: hematologist

Overview:

Certainly! The California Blood Bank Society (CBBS) held its 2022 Annual Meeting as a virtual event on June 3-4, 2022. Here are the details:

• Agenda: The preliminary agenda included presentations from subject matter experts covering a wide range of topics in Transfusion Medicine and Cell Therapy. Some of the topics discussed were cold stored platelets, cellular therapy, pre-hospital transfusions, monoclonal antibody treatments, and transfusion medicine cases.
• Target Audience: Physicians, nurses, and laboratory professionals were the intended audience for this meeting.

 

*Note: these are continuous video recordings during the conference, they include individual lectures mentioned in the Detail section below

CBBS-_Annual_Meeting_-_Agenda (PDF Format)

June 3 (Video MP4 Format) (7 hours)

June 4 (Video MP4 Format) (6 hours)

 

*Detail:

JUNE 3, 2022

8:00 am – Welcome to 2022 CBBS Annual Meeting – CBBS President Suchitra Pandey*

8:05 am – Perkins-Garratty Award Lecture: Prospective Antigen Matching: Effectiveness, Diversity and Equity Dr. Meghan Delaney, DO, MPH

Objectives:

• Explain the impact of prophylactic antigen matching on new RBC alloimmunization in patients with warm autoantibodies.

• Compare different approaches for antigen matching for females and its impact on hemolytic disease of the fetus and newborn (HDFN).

• Relate how the diversity of the patient population may determine access to antigen-matched transfusions and HDFN care.

9:05 am – Cold-Stored Platelets: Current Use and Future Prospects – Dr. James R. Stubbs, MD

Objectives:

• Summarize the differences between cold-stored platelets and room-temperature platelets that should drive preferential use of these products in selected patient populations.

• Illustrate a current use of cold-stored platelets

• Appraise an ongoing research project that could potentially result in the expanded use of cold-stored platelets to benefit patient populations who are not currently receiving these components as part of their care.

10:02 am – Strategies to Maintain an Adequate Platelet Supply – Dr. Suchitra Pandey, MD

Objectives:

• Assess two reasons why the current state of the platelet supply is at risk of critical shortages.

• Examine two strategies to grow the donor pool and increase production of platelets.

10:40 am – Break*

10:45 am – For Here or To-Go? Discussing transfusion in transport. – Michael Baulch, RN, JD & Lee McMurray, MSN

Objectives:

• Examine transfusion needs of critical trauma and medical patients in transport.

• Analyze resuscitation options currently in practice, and their outcomes.

• Compare the benefits of blood component therapy versus whole blood transfusion during transport.

11:30 am – Leadership and Partnership During a National Blood Crisis: Getting Through the Crisis Together – Ross Herron, MD, Divisional Chief Medical Officer, American Red Cross Blood Services & Sarah Barnhard, MD FCAP FASCP, Associate Professor UC Davis

Objectives:

• Contrast three management and allocation strategies implemented by a blood supplier during the largest blood shortage in the past decade

• Summarize the crucial partnership between a hospital and their blood supplier to manage the blood shortage

• Describe the role blood center and hospital leadership played in addressing this national blood crisis.

12:00 pm – Meeting the Transfusion Needs of Patients With Sickle Cell Disease: It’s About Addressing Health Disparities and Access To Donation – Yvette Marie Miller, M.D., ABIHM, & Executive Medical Officer American Red Cross

Objectives:

• Choose at least two effective strategies to increase the recruitment of African American blood donors

• Summarize the important role donor recruitment plays in supporting transfusion needs of sickle cell patients.

12:30 pm – Lunch*

1:00 pm – Auto- vs. alloantibody in a patient with thalassemia – Ariela Edelman, MLS (ASCP)

Objectives:

• Outline the genetics of the Kidd blood group system

• Contrast how molecular methods can be used to distinguish between auto- vs. alloanti-Jka antibodies

• Summarize the limitations of multiple immunohematology testing methodologies

1:22pm – False anemia due to total parenteral nutrition and lipid emulsion contamination – Bethelhem Manakelew

Objectives:

• Analyze the potential for contamination when collecting blood samples.

• Evaluate one facility’s protocol for collecting uncontaminated blood samples.

• Determine the signs of false anemia due to lipid contamination

1:44pm – Therapeutic Response to Apheresis Aids Diagnosis of an Occult Malignancy – Dr. Hehua (Hannah) Huang, MD

Objectives:

• Identify a syndrome that can have several etiologies, including paraneoplastic processes.

• Outline paraneoplastic neurologic disorders (PND).

• Predict common applications of therapeutic apheresis.

2:06pm – Complex Antibody Identification Case Study – Rebecca (Becky) Thomas, MT (ASCP) SBB

Objectives:

• Explain the significance of testing phenotype-matched cells when all test cells are positive and the patient’s auto-control is negative.

• Differentiate two test methods used to facilitate identification of antibodies to high-incidence antigens.

• Appraise the monocyte monolayer assay (MMA).

2:30 pm – Business Meeting*

3:15 pm – Closing Remarks*

 

 

June 4, 2022

8:00 am – Welcome and Presentations of the Upton/Hemphill and Thomas Award*

8:15 am – Dr. Goldfinger Tribute – Samuel Pepkowitz, MD, and Louise Smith MPA, MT(ASCP)SBB

8:30 am – Dr. Dennis Goldfinger Award Lecture: Pearls of Wisdom from a Lifelong Fellowship/Friendship with Dr. Dennis Goldfinger – Dr. James Burner, MD

Objectives:

• Describe three clinical and laboratory findings in hyperhemolysis of sickle cell disease.

• Summarize the “two-hit” hypothesis of transfusion-related acute lung injury (TRALI).

• Analyze the potential risk of transfusion-transmitted cytomegalovirus (CMV)

9:15 am – Phasing in RHD Genotyping: Impact on Transfusion Practices – Sunitha Vege, MS

Objectives:

• Compare the different classifications of RHD alleles.

• Outline the strengths and limitations of current molecular methods utilized to identify RHD alleles.

• Conclude the impact of phasing in RHD genotyping on transfusion practices for patients with altered RHD alleles.

10:00 am – Monoclonal antibody interference in blood bank testing – Janet Baez, MT (ASCP)

Objectives:

• Identify two indications for monoclonal antibody therapy

• Examine monoclonal antibody interference in blood bank testing

• Formulate testing options available to resolve monoclonal antibody interference in blood bank testing

10:45 am – Break*

10:55 am – Susanne Ledin Award Lecture: Effective and Efficient Complex Serologic Antibody Identification (OR: Whoa, What Happens after the 3rd Panel?) – Sandra Nance, MS, MASCP, MT(ASCP)SBB

Objectives:

• Describe a complex antibody presentation that may require further investigation.

• Explain how the process of complex antibody identification can be optimized.

• Determine when a complex case resolution exceeds their laboratory’s ability to complete.

11:40 am – New Frontier in Cell Therapy – Dr. Mehrdad Abedi, MD

Objectives:

• Relate at least 2 different disease groups which can be treated with CAR-T cell therapy.

• Outline some of the potential complications of CAR-T cell therapy.

• Identify some of the potential side effects of gene therapy.

12:25 pm – Lunch*

1:05 pm – Polyclonal Regulatory T cell Manufacturing under cGMP: A Decade of Experiences – Dr. Joanna Balcerek, MD, PhD

Objectives:

• Break down key aspects of regulatory T cell manufacturing

• Explain how the quality of regulatory T cell products is assessed

• Compare the impact of independent variables on regulatory T cell manufacturing outcomes

1:35 pm – Ask the Experts – Various Speakers/experts – Moderated by scientific committee chairs

• Compare various opinions offered by expert speakers and resolve unanswered questions

2:35 pm – Closing Remarks*