ASTRO Multidisciplinary Head and Neck Cancers Symposium 2022

ASTRO Multidisciplinary Head and Neck Cancers Symposium 2022

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American Society for Radiation Oncology Multidisciplinary Head and Neck Cancers Symposium 2022

Format: 5 videos + 1 pdf, size: 34.1 GB

Course Audience: medical oncologists, radiation oncologists, surgeons, physicists, nurses, diagnostic radiologists, pathologists, radiation therapists, radiation dosimetrists, speech language pathologists/scientists, dentists, oral surgeons, swallowing and speech therapists, audiologists, physical therapists, scientists, immunologist and rehabilitation specialists

Agenda (PDF Format)

Thursday, February 24, 2022 Part 1 (Video MP4 Format)

Thursday, February 24, 2022 Part 2 (Video MP4 Format)

Friday, February 25, 2022 Part 1 (Video MP4 Format)

Friday, February 25, 2022 Part 2 (Video MP4 Format)

Saturday, February 26, 2022 (Video MP4 Format)

 

* Detail:

Wednesday, February 23, 2022

4:00 p.m. – 6:00 p.m. Registration Open

Thursday, February 24, 2022

7:00 a.m. – 4:30 p.m. Registration Open
7:00 a.m. – 8:00 a.m. Continental Breakfast
7:50 a.m. – 8:00 a.m. Day One Welcome

Cherie-Ann Nathan, MD, Louisiana State University-Health, Shreveport, Louisiana [HNS]
8:00 a.m. – 8:20 a.m. Patient Perspective: Building a Community of HNL Patients, Coaches and Mentors

Speaker: Michael West
8:20 a.m. – 9:50 a.m. Patient-centric Head and Neck Care 

Moderator: Cherie-Ann Nathan, MD, Louisiana State University-Health, Shreveport, Louisiana [HNS]

  • Comprehensive Rehabilitation of the Head and Neck Patient

    • Heather Starmer, MA, CCC-SLP, BCS-S, Stanford University, Stanford, California [SLP]

  • Oral/Dental Needs in HNC Survivors

    • Joel Epstein, DMD, MSD, Cedars-Sinai, Los Angeles [OMFS]

  • Addressing the Psychological Aspects of Head and Neck Cancer

    • Elizabeth Cash, PhD, University of Louisville, Louisville, Kentucky [Psychologist]

  • The Artistry of Facial Prosthetics

    • Devin Okay, DDS, Mount Sinai Hospital, New York [OMFS]

  • Nutrition in Head and Neck Cancer

    • Patricia Rubio, MBA, MS, University of California, San Diego [Nutritionist]

  • Questions and Answers

9:50 a.m. – 10:35 a.m. Keynote I: Disparities in Head and Neck Cancer

Moderator: Dan Zandberg, MD, University of Pittsburgh Medical Center, Pittsburgh [M]

  • Sharon Spencer, MD, University of Alabama at Birmingham, Birmingham, Alabama [R]
  • Charles Moore, MD, Emory University, Atlanta [HNS]

10:35 a.m. – 11:00 a.m. Coffee Break
11:00 a.m. – 12:30 p.m. Escalation Strategies and Novel Approaches in Locally Advanced Head and Neck Cancer

Moderator: Julie Bauman, MD, MPH, University of Arizona, Tucson, Arizona [M]

  • Immunotherapy in the Curative Intent Setting

    • Sana Karam, MD, PhD, University of Colorado, Denver [R]

  • The Role of Preop IO in Locally Advanced HNC

    • Ravi Uppaluri, MD, PhD, Brigham and Women’s Hospital, Boston [HNS]

  • Novel Radiosensitizers

    • Heath Skinner, MD, PhD, University of Pittsburgh,  Pittsburgh [R]

  • Nasopharynx: Induction vs Adjuvant – Where do we go from here?

    • Dimitrios Colevas, MD, Stanford University, Stanford, California [M]

  • Questions and Answers

12:30 p.m. – 1:30 p.m. Lunch in the Exhibit Hall

Early-career and Trainee Networking Luncheon: Choosing Your Career Path

Highlight careers briefly at the beginning and then break out into small groups at the different round tables.

Moderator: Maie St. John, MD, PhD, UCLA David Geffen, Los Angeles [HNS]

  • Julie Bauman, MD, MPH, University of Arizona, Tucson, Arizona [M]
  • Katherine Hutcheson, PhD, MD Anderson Cancer Center, Houston [Speech Path]
  • Faye Johnson, MD, PhD, MD Anderson Cancer Center, Houston [M]
  • Loren Mell, MD, University of California, San Diego [R]
  • Maie St. John, MD, PhD, UCLA David Geffen, Los Angeles [HNS]

1:30 p.m. – 3:00 p.m. K. Kian Ang, MD, PhD, FASTRO, Commemorative Plenary Session

Moderator: Maie St. John, MD, PhD, UCLA David Geffen, Los Angeles [HNS]

  • Early Toxicity and Patient Reported Outcomes from a Phase 2 Trial of FDG-PET Response-based De-escalated Definitive Radiotherapy for p16+ Oropharynx Cancer

    • Steven Allen, University of Michigan, Ann Arbor, Michigan

  • Non-inferiority Margin and Nodal Analysis of De-escalated Adjuvant Radiation Therapy (DART) for HPV-related Oropharyngeal Squamous Cell Carcinoma (OPSCC): A Preplanned Pooled Analysis of MC1273 & MC1675

    • Daniel Ma, Mayo Clinic, Rochester, Minnesota

  • Detection of Occult Recurrence Using Circulating HPV Tumor DNA among Patients Treated for HPV-driven Oropharyngeal Squamous Cell Carcinoma

    • Glenn Hanna, Dana-Farber Cancer Institute, Harvard Medical School, Boston

  • Kinetics of Circulating Human Papillomavirus (cHPV) DNA in Plasma and Oral Gargles from Patients with HPV-positive Oropharyngeal Cancer (OPC) Treated with Definitive Radiation Therapy

    • Michelle Echevarria, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida

  • A Clinically Translatable, Extensively Validated Immune-based Classification of Human Papillomavirus-associated Head and Neck Cancer with Implications for Treatment Deintensification and Immunotherapy

    • Peter Zeng, Western University, London, Ontario, Canada

  • Predicted Th2 Infiltrate is Associated with Outcome in HPV(-) Head and Neck Cancer

    • Mohamed Abdelhakiem, UPMC Hillman Cancer Center, Pittsburgh

  • Loss of HPV 16- E2 Predicts Disease Free Survival and Promotes Platinum Resistance in Human Papillomavirus-Positive Head and Neck Squamous Cell Carcinoma

    • Molly Heft-Neal, University of Michigan, Ann Arbor, Michigan

  • Neoadjuvant Immunoradiotherapy in a Tobacco-Signature Preclinical Oral Squamous Cell Carcinoma Model

    • Robert Saddawi-Konefka, University of California, San Diego

  • HPV E5 Mediates Resistance to PD-1 Checkpoint Blockade via Inhibition of MHC and IFN Pathway

    • Andrew Sharabi, University of California, San Diego

3:00 p.m. – 3:30 p.m. Coffee Break
3:30 p.m. – 4:30 p.m. Case Study and Debate: Curative Intent in Elderly and Frail

Moderator: Zain Husain, MD, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada [R]

  • Susan McCammon, MD, University of Alabama, Birmingham, Birmingham, Alabama [HNS]
  • Loren Mell, MD, University of California, San Diego [R]
  • Paul Loren Swiecicki, MD, University of Michigan, Ann Arbor, Michigan [M]
  • Questions and Answers

4:30 p.m. – 5:30 p.m. Research Feature and Networking Reception

Friday, February 25, 2022

7:00 a.m. – 5:30 p.m. Registration Open
7:00 a.m. – 8:00 a.m. Continental Breakfast
7:55 a.m. – 8:00 a.m. Day Two Welcome

Quynh-Thu Le, MD, FASTRO, Stanford University, Stanford, California [R]
8:00 a.m. – 8:20 a.m. Patient Perspective

Speaker: Andy Pluemer
8:20 a.m. – 9:40 a.m. HOT TOPIC: Early Oral Cavity

Moderator: Mike Moore, MD, Indiana University of Medicine, Indianapolis [HNS]

  • Tumor Board
  • Intraoperative Margin Assessment

    • Mark Varvares, MD, FACS, Massachusetts General Hospital, Boston [HNS]

  • Pathologist’s Perspective

    • Margaret Brandwein-Weber, MD, Mount Sinai, New York [Pathologist]

  • Sentinel Node and Neck Dissection

    • Stephen Lai, MD, PhD, FACS, MD Anderson Cancer Center, Houston [HNS]

  • New Frontiers in Sx: Fluorescence Guided Sx

    • Eben Rosenthal, MD, Vanderbilt University Medical Center, Nashville [HNS]

  • Surgical Reconstruction

    • Kelly Malloy, MD, University of Michigan, Ann Arbor, Michigan [HNS]

9:40 a.m. – 10:25 a.m. Keynote II: Towards Personalization of HPV Related Oropharyngeal Carcinoma

Moderator: Quynh-Thu Le, MD, FASTRO, Stanford University, Stanford, California [R]

Speaker: Nancy Lee, MD, FASTRO, Memorial Sloan Kettering Cancer Center, New York [R]
10:25 a.m. – 10:50 a.m. Coffee Break
10:50 a.m. – 12:20 p.m. Plenary II

Moderator: Alexander Pearson, MD, PhD, University of Chicago, Chicago [M]

  • An Artificial Intelligence Ultrasound Platform for Screening and Staging of Thyroid Cancer

    • Annie Chan, Massachusetts General Hospital, Harvard Medical School, Boston

  • Development of a Deep Learning-based Auto-segmentation of Organs at Risk for Head and Neck Radiotherapy Planning

    • Jihye Koo, University of South Florida, Tampa, Florida

  • Safety and Efficacy of RP1 + Nivolumab in Patients with Non-melanoma Skin Cancer of the Head and Neck: Results From IGNYTE Phase 1/2 Multi-cohort Clinical Trial

    • Jiaxin Niu, Banner MD Anderson Cancer Center, Houston

  • A Novel Intratumoral Microdosing Approach for Simultaneously Evaluating Multiple Drugs and Combinations in Patients with Head and Neck Squamous Cell Carcinoma (HNSCC)

    • Harrison Cash, University of Washington Medical Center, Seattle

  • Efficacy and Safety of Tisotumab Vedotin in Patients with Head and Neck Squamous Cell Carcinoma: Results from a Phase II Cohort

    • May Cho, MD, University of California, Irvine, CA

  • Stereotactic Ablative Radiotherapy for Early-stage Glottic Larynx Carcinoma: Results from the Phase II LT-SABR Study

    • David Sher, University of Texas Southwestern Medical Center, Dallas

  • Standard but Not Equal: Disparities in Advanced Radiotherapy Techniques for Head and Neck Cancer in the United States

    • Neal McCall, Winship Cancer Institute of Emory University, Atlanta

  • Focal Adhesion Kinase Drives Resistance to Therapy in HPV-Negative Head and Neck Squamous Cell Carcinoma in a P53-Dependent Manner

    • Phillip Pifer, UPMC Hillman Cancer Center, Pittsburgh

12:20 p.m. – 1:20 p.m. Lunch in the Exhibit Hall

Early-career and Trainee Networking Luncheon: Launching Your Successful Career

  • How to Get Your Paper Published

    • Renata Ferrarotto, MD, MD Anderson Cancer Center, Houston, Texas [M]

  • Finding Personal/Professional Balance

    • Cherie-Ann Nathan, MD, Louisiana State University-Health, Shreveport, Louisiana [HNS]

  • Seeking Out and Maintaining Mentoring Relationships

    • Zain Husain, MD, Sunnybrook Health Sciences Centre, Ontario, Canada [Dermatologist]

1:20 p.m. – 2:35 p.m. Panel: Thyroid

Moderator: Sue Yom, MD, PhD, FASTRO, University of California, San Francisco [R]

  • Mutational Landscape of Thyroid Cancers

    • Nabil Saba, MD, FACP, Winship Cancer Institute of Emory University, Atlanta [M]

  • Low Risk Thyroid Cancer/RAI

    • Jennifer Sipos, MD, The Ohio State University, Columbus, Ohio [Endocrinologist]

  • Therapies for High Risk and Anaplastic Thyroid Cancer

    • Saad Khan, MD, Stanford University, Stanford, California [M]

  • Multimodality Therapy for Aggressive Differentiated Thyroid Cancers

    • Mark Zafereo, MD, FACS, MD Anderson Cancer Center, Houston [HNS]

2:35 p.m. – 3:00 p.m. Coffee Break
3:00 p.m. – 4:30 p.m. HOT Topic: Options in Advanced Skin Squamous Cell Carcinoma

Moderator: Robert Ferris, MD, PhD, University of Pittsburgh [R]

  • Controversies in Surgical Management

    • Cecelia Schmalbach, MD, MSc, FACS, Temple Health, Philadelphia [HNS]

  • Role of Radiation

    • ​Shlomo Koyfman, MD, Cleveland Clinic, Cleveland [R]

  • Systemic Therapy

    • Jessica Geiger, MD, Cleveland Clinic Cancer Center, Cleveland [M

  • Immunotherapy in Special Populations

    • Anne Chang, MD, Stanford University, Stanford, California [Dermatologist]

  • Questions and Answers

4:30 p.m. – 5:30 p.m. Development of Survivorship Programs

Moderator: Jon Irish, MD, MSc, FRCSC, FACS, University of Toronto, Toronto, Ontario,Canada [HNS]

  • Developing Care Pathways

    • Liza Blumenfeld, MA, CCC-SLP, BCS-S, University of California, San Diego [SLP]

  • Practice and Research

    • Marci Lee Nilsen, PhD, RN, University of Pittsburgh, Pittsburgh [RN]

  • Financial Toxicity

    • Jonas de Souza, MD, MBA, HCA Healthcare, Nashville [M]

  • Questions and Answers

Saturday, February 26, 2022

7:00 a.m. – 12:15 p.m. Registration Open
7:00 a.m. – 8:00 a.m. Continental Breakfast
7:55 a.m. – 8:00 a.m. Day Three Welcome

Faye Johnson, MD, PhD, MD Anderson Cancer Center, Houston [M]
8:00 a.m. – 8:20 a.m. Patient Perspective

David Burkett
8:20 a.m. – 9:45 a.m. De-escalation for HPV

Moderator: Katherine Hutcheson, PhD, MD Anderson Cancer Center, Houston, [SLP]

  • Introduction

    • Katherine Hutcheson, PhD, MD Anderson Cancer Center, Houston [SLP]

  • Surgical Considerations

    • Umamaheswar Duvvuri, MD, PhD, University of Pittsburgh, Pittsburgh [HNS]

  • Radiation Considerations

    • Bhisham Chera, MD, UNC School of Medicine, Chapel Hill, North Carolina [R]

  • Systemic Considerations

    • Neil Hayes, MD, The University of Tennessee Health Science Center, Memphis, Tennessee [M]

  • Questions and Answers

9:45 a.m. – 10:30 a.m. Salivary Cancers

Moderator: Assuntina Gesualda Sacco, MD, University of California, San Diego, Moores Cancer Center, La Jolla, California [M]

  • Current Approaches to Managing Salivary Cancer

    • Kiran Kakarala, MD, University of Kansas Medical Center, Kansas City, Kansas [HNS]

  • Novel Systemic Treatment for Recurrent or Metastatic Salivary Cancers

    • Renata Ferrarotto, MD, MD Anderson Cancer Center, Houston [M]

  • Questions and Answers

10:30 a.m. – 10:45 a.m. Coffee Break
10:45 a.m. – 12:15 p.m. Recurrent and Metastatic Head and Neck Cancer

Moderator: Farzan Siddiqui, MD, PhD, Henry Ford Cancer Institute, Detroit [R]

  • Re-irradiation for Recurrent and Second Primary Head and Neck Cancers

    • Neal Dunlap, MD, University of Louisville, Louisville, Kentucky [R] ​

  • Surgical Salvage with Reconstruction

    • Urjeet Patel, MD, Northwestern Hospital, Chicago [HNS]

  • Novel Targeted and Immunotherapies

    • Christine Chung, MD, Moffitt Cancer Center, Tampa, Florida [M]

  • Case Discussions