Penn Penn HFpEF Symposium 2023

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Penn Medicine UPenn HFpEF Symposium 2023

Format: 39 videos + 35 pdfs, size: 15.3 GB

Course Audience: cardiologist, pulmonologist, radiologist, endocrinologist, sleep medicine physician

Overview:

Date & Location

Friday, March 24, 2023, 8:00 AM – Saturday, March 25, 2023, 7:20 PM, Smilow Center and Online, Philadelphia, PA

Course Overview

While the incidence of heart failure with reduced ejection fraction (HFrEF) has decreased, that of heart failure with preserved ejection fraction (HFpEF) continues to rise, accounting for ~50% of heart failure hospitalizations. Patients with HFpEF suffer mentally and physically, similar to their HFrEF counterparts, and are markedly limited in terms of their functional capacity and quality of life. Yet in contrast to HFrEF, there are few effective pharmacologic treatments for HFpEF, despite numerous clinical trials.

To address this urgent need, many clinicians and researchers have focused on this important medical and societal issue. Improved strategies now exist to diagnose this condition, and multifaceted treatment options can help to alleviate some of the morbidity of the disease. This symposium will highlight diagnostic strategies and review the evidence base for pharmacologic therapies. Treatment of comorbid conditions found in HFpEF patients will also be discussed. Additional didactics highlighting the sources of exertional intolerance in HFpEF patients will be presented, with an emphasis on cardiopulmonary exercise testing.

The topics chosen for this conference represent the state-of-the-art in HFpEF management, incorporating the expertise of numerous disciplines including cardiology, pulmonology, radiology, sleep medicine, and endocrinology. The meeting is intended to provide an in-depth summary of HFpEF management to practicing clinicians across numerous disciplines, including Physicians, Nurse Practitioners, and Physician Assistants.

Target Audience

Specialties – FAMILY MEDICINE, INTERNAL MEDICINE, INTERNAL MEDICINE – Advanced Heart Failure and Transplant Cardiology

Learning Objectives

After completing this activity, participants should be able to:

  1. Review the diagnostic criteria for HFpEF, including when to use advanced imaging or hemodynamic assessment
  2. Discuss HFpEF mimickers, including amyloidosis, sarcoidosis, and inherited cardiomyopathies
  3. Discuss the role of non-cardiac structures (such as the arterial system and other organs) in the pathogenesis and treatment of HFpEF
  4. Describe the electrophysiologic manifestations of HFpEF and their treatments
  5. Discuss novel therapies that are on the horizon for HFpEF
  6. Review the potential causes of exertional intolerance in HFpEF patients.

Acute nitroglycerin use worsens ventilatory efficiency during exercise in patients with heart failure with preserved ejection fraction (Video MP4 Format)

Addressing Disparities in the Management of HFpEF and its Comorbidities (Video MP4 Format)

Addressing Disparities in the Management of HFpEF and its Comorbidities (PDF Format)

Advanced Echo Techniques to Diagnose HFpEF (Video MP4 Format)

Advanced Echo Techniques to Diagnose HFpEF (PDF Format)

Advanced Imaging – PET and cMRI in HFpEF (Video MP4 Format)

Advanced Imaging – PET and cMRI in HFpEF (PDF Format)

Atrial Fibrillation in HFpEF – Should We Ablate Sooner. (Video MP4 Format)

Atrial Fibrillation in HFpEF – Should We Ablate Sooner. (PDF Format)

Case Presentation – Cardiology Fellows Junior Faculty 2 (Video MP4 Format)

Case Presentation – Cardiology Fellows Junior Faculty 2 (PDF Format)

Case Presentation – Cardiology Fellows Junior Faculty (Video MP4 Format)

Case Presentation – Cardiology Fellows Junior Faculty (PDF Format)

Case Presentation- HF Cardiology Fellow 2 (Video MP4 Format)

Case Presentation- HF Cardiology Fellow 2 (PDF Format)

Case Presentation- HF Cardiology Fellow (Video MP4 Format)

Case Presentation- HF Cardiology Fellow (PDF Format)

Chronotropic Incompetence- Modulating Sinus Rhythm and Pacing (Video MP4 Format)

Chronotropic Incompetence- Modulating Sinus Rhythm and Pacing (PDF Format)

Clinical Factors and Biomarkers – Scoring Systems (e.g. H2FPEF) (Video MP4 Format)

Clinical Factors and Biomarkers – Scoring Systems (e.g. H2FPEF) (PDF Format)

Debate- It’s the Heart! High Pressures ‘Limit’ Exercise in HFpEF (Video MP4 Format)

Debate- It’s the Heart! High Pressures ‘Limit’ Exercise in HFpEF (PDF Format)

Debate- The Heart Isn’t Normal but It’s Not Everything – Peripheral Limitations in HFpEF (PDF Format)

Development of novel mouse models recapitulating Heart Failure with preserved Ejection Fraction (Video MP4 Format)

Diuretics and Overcoming Resistance (Video MP4 Format)

Diuretics and Overcoming Resistance (PDF Format)

Drugs to Modulate Contractility – Levosimendan and Mavacamten (Video MP4 Format)

Drugs to Modulate Contractility – Levosimendan and Mavacamten (PDF Format)

EpiProteomic Profiling Of Human Heart Biopsies Reveals Histone H3k27acMediated Metabolic Dysfunction In Heart Failure With Preserved Ejection Fraction (Video MP4 Format)

Exercise Physiology, as seen Through a CPET Test (Video MP4 Format)

Exercise Physiology, as seen Through a CPET Test (PDF Format)

Fibrosis In HFpEF – What it Means and What to do About it. The New and the Old (Video MP4 Format)

Fibrosis In HFpEF – What it Means and What to do About it. The New and the Old (PDF Format)

HFpEF Epidemiology – a Growing Problem (Video MP4 Format)

HFpEF Epidemiology – a Growing Problem (PDF Format)

HFpEF – A Global Perspective (Video MP4 Format)

HFpEF – A Global Perspective (PDF Format)

HFpEF23_Brochure_v24 (PDF Format)

Implantable PA Monitors in HFpEF (Video MP4 Format)

Implantable PA Monitors in HFpEF (PDF Format)

Intracardiac Shunt Devices (Video MP4 Format)

Intracardiac Shunt Devices (PDF Format)

Keynote- HFpEF Guidelines – Phenogroups to Guide Therapies (Video MP4 Format)

Keynote- HFpEF Guidelines – Phenogroups to Guide Therapies (PDF Format)

Keynote- Redefining the Pathobiology of HFpEF (Video MP4 Format)

Keynote- Redefining the Pathobiology of HFpEF (PDF Format)

Keynote- The Future of HFpEF Treatment (PDF Format)

Lung Disease and Pulmonary Hypertension in HFpEF (Video MP4 Format)

Lung Disease and Pulmonary Hypertension in HFpEF (PDF Format)

Management of Obesity – Drugs and Surgical Considerations (Video MP4 Format)

Management of Obesity – Drugs and Surgical Considerations (PDF Format)

Mechanisms limiting stroke volume reserve in patients with HFpEF- the potential role of interventricular dependence in the upright position (Video MP4 Format)

Microvascular Dysfunction in HFpEF (Video MP4 Format)

Microvascular Dysfunction in HFpEF (PDF Format)

MRAs and ARNIs – Trials, Tribulations, and Recommendations (Video MP4 Format)

MRAs and ARNIs – Trials, Tribulations, and Recommendations (PDF Format)

Overcoming the Sedentary Lifestyle – Exercise as Prevention and Treatment for HFpEF (Video MP4 Format)

Overcoming the Sedentary Lifestyle – Exercise as Prevention and Treatment for HFpEF (PDF Format)

Paracardial fat is related to adverse ventricular interdependence in heart failure with preserved ejection fraction (Video MP4 Format)

Recap of Day 1 and Intro to Day 2 (Video MP4 Format)

Recap of Day 1 and Intro to Day 2 (PDF Format)

Regulation Of Skeletal Muscle Blood Flow And Oxygen Utilization In Heart Failure With Preserved Ejection Fraction During Small Muscle Mass Exercise (Video MP4 Format)

SGLT2i- Outcomes and Controversies (Video MP4 Format)

SGLT2i- Outcomes and Controversies (PDF Format)

Sleep Apnea in HFpEF (PDF Format)

Splanchnic Nerve Modulation in HFpEF (Video MP4 Format)

Splanchnic Nerve Modulation in HFpEF (PDF Format)

To the Cath Lab – Manuevers and Challenges to Make the Diagnosis and When to Biopsy (Video MP4 Format)

To the Cath Lab – Manuevers and Challenges to Make the Diagnosis and When to Biopsy (PDF Format)

Update on Amyloid Therapies (Video MP4 Format)

Update on Amyloid Therapies (PDF Format)

Vasohibin Inhibition Improves Relaxation Kinetics in a Rodent Model of HFpEF (Video MP4 Format)

Wholebody macronutrient tracing in a mouse model of heart failure with preserved ejection fraction (Video MP4 Format)

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