Memorial Sloan Kettering Cancer Center The Robert Steel Symposium in Developmental Oncology 2022
Format: 5 videos + 6 pdfs, size: 441 MB
Course Audience: oncologist, primary care physician
Overview:
Date & Location
Monday, May 2, 2022, 8:30 AM – Tuesday, May 3, 2022, 2:00 PM, Zuckerman Research Center, 417 East 68th Street, New York, NY
Specialties
Specialties – Bone Marrow Transplant, Breast Medical Oncology, Cellular Therapeutics, Computational Biology, Epidemiology, Gastrointestinal Oncology, Genetics, Genitourinary Oncology, Gynecologic Oncology, Head and Neck Oncology, Hematology, Immigrant Health and Cancer Disparities, Immunotherapy, Internal Medicine, Laboratory Medicine, Leukemia, Lymphoma, Medical Oncology, Molecular Biology, Neuro-Oncology, Neurosurgery, Oncology and Hematology, Orthopedic Surgery, Pediatrics, Radiation Oncology, Solid Tumor Oncology, Surgical Oncology, Thoracic Medical Oncology
Overview
The Robert Steel Symposium in Developmental Oncology will bring together outstanding scientists from across the country to discuss the latest discoveries into the molecular mechanisms of cancers in children and young adults and the development of new approaches for their definitive therapy and control. The symposium is the first of its kind which is dedicated to new science at the interface of human development and cancer pathogenesis. This program will feature interactive discussions of fundamental and translational research to address unanswered questions in the field of developmental oncology.
There are many unanswered questions that need to be addressed for childhood and young adult cancers:
- What causes cancer in children and young adults without inheritance of cancer-predisposing mutations or exposure to environmental mutagens? How do predisposing alleles and exposures contribute to cancer development?
- What developmental processes are dysregulated to cause mutations and cell transformation in otherwise healthy tissues?
- How do mutations in developmental pathways involving transcription factors and epigenetic signaling cause cancer?
- How do we design effective therapeutics to block, activate, and modulate protein interactions that control transcription factors and other developmental regulators?
- How do we identify targets for immune therapy in developmental tumors that have relatively few mutations?
This two-day live in-person symposium will provide an intimate and exciting setting to share new advances for these questions. It will also allow an opportunity for established and young investigators to discuss new questions and interdisciplinary approaches of relevance to young-onset cancer biology.
Who Should Attend
The target audience for this symposium includes scientists, physicians, APPs, nurses, and other healthcare providers interested in learning the latest advances in our understanding of the biology and therapy of childhood cancers.
The MSK CME team is closely monitoring the impact of COVID-19 on our ability to host in-person events. We thank you for your cooperation as we work together to meet the challenges posed by COVID-19. All registrants will be notified if there are any changes. Your health and safety, and that of our patients and employees, is our highest priority.
Please note that we do hope to host a reception/dinner for attendees on Monday, May 2, pending COVID-19 restrictions. If you are interested in attending a possible reception/dinner, please let us know during registration so we can plan accordingly.
Objectives
- Explain biologic and developmental causes of childhood cancers.
- Review recently developed therapies for patients with childhood and young-onset cancers.
- Discuss new biologic questions in order to accelerate the development of definitive therapies for patients.
A CD24-directed T cell-engaging bispecific antibody for demoplastic small round cell tumor (Video MP4 Format)
A CD24-directed T cell-engaging bispecific antibody for demoplastic small round cell tumor (PDF Format)
A human pluripotent stem cell derived human in vitro differentiation model for the study of normal and transformed sympatho-adrenal development. (Video MP4 Format)
A human pluripotent stem cell derived human in vitro differentiation model for the study of normal and transformed sympatho-adrenal development. (PDF Format)
Centrosomal Vulnerabilities In ZFTA-Rela Ependymoma (Video MP4 Format)
Centrosomal Vulnerabilities In ZFTA-Rela Ependymoma (PDF Format)
DevOnc2022_Brochure (PDF Format)
Exploring cell-cell communication networks in medulloblastoma using single-cell genomics (Video MP4 Format)
Exploring cell-cell communication networks in medulloblastoma using single-cell genomics (PDF Format)
Towards rational epigenetic combination therapy based on the mechanisms of clinical resistance to EZH2 inhibition in BAF-deficient sarcomas (Video MP4 Format)
Towards rational epigenetic combination therapy based on the mechanisms of clinical resistance to EZH2 inhibition in BAF-deficient sarcomas (PDF Format)